[ Patrick Henry would have been an anti-vaxxer. ]
Indeed he would!
Patrick Henry was vaccinated against smallpox which was the only vaccination available in the 1700s. I think he would have been pro vaccines; after all, he was a man of reason in the Age of Reason not a Luddite. I think, though, that he probably agree with parents who do not want their young child’s immune system overwhelmed all at once with too many vaccines.