Your figure contains too many zeroes.
Most deaths were by disease and that was absolutely unavoidable. Technology made global travel and the spread of diseases worldwide possible.
The technology genie wasn't going back inside the bottle. If it wasn't Europeans introducing new diseases into the New World, it would have been someone else... probably the muslims.
As bad as you may believe Europeans to have been relative to our present time, try imaging a New World colonized by muslims.
You like any of the 2000+ mosques across America?
You MEAN like any of the 2000+ mosques across America?