So far as I've been able to figure out, there are currently no federal regulation concerning the size mud flaps.
There was talk of imposing such regulations in the Nineties, but apparently it didn't go through.
States decide those regulations.
So all that secession and civil war were unnecessary.
* sigh *
The federal government began to take control of the flap about mud flaps in Bibb v Navajo Freight Lines.
Commerce clause was the reason given. Patrick Henry spoke of the importance of the federal rule of mud flaps many times.