The Big Bang Theory ending because Jim Parsons was ready to leave
https://ew.com/tv/2018/08/22/the-big-bang-theory-ending-jim-parsons-ready-to-leave/
Imagine turning down $1,000,000 an episode for working less then 30 minutes because you are bored.
Most of the cast will disappear. Hollywood people are jealous when someone is successful even though they want the success for themselves. They won’t hire them in any good roles and watch them take mediocre roles like Penny in “Serial Ape-ist 2: Monkey See, Monkey Kill”
https://www.youtube.com/watch?v=FdajsDAh7kc