Nylon 66-great .22.
I have not tried it. My Sig will not shoot anything Rem 22LR old school.
When my son was in college he fished my 35+-year-old Nylon 66 out of the closet and asked if he could clean it up and send a few rounds through it. A couple of weeks later he told me that ancient, un-maintained relic from my own youth was the hit of the rifle range when he cleaned it up and took it out for a shooting.
It looked like new when he returned it to me, and I just handed it back and said .. "Now it's yours".
That was an amazing survival rifle, BTW. Extremely light weight and rugged, and the perfect round for taking out small game.
Mohawk. Great shooting rifle.