The bloodbath in the Virginia HoD maybe a foretaste of what is going to happen in the Ryan led House of Representatives in 2018. The GOPe is setting up for a disaster and could lose both the House and the Senate. The Uniparty would probably be satisfied with that and then they could get on with fully crippling or removing Trump.
Will that scenario happen in all HOR races? No, but the R will remain in the majority in the HOR.