One small issue that seems to be universally ignored is that the federal government has absolutely no constitutional authority to prohibit drugs in the first place.
Why doesn’t anyone ever ask why it took a constitutional amendment for the federal gov’t to prohibit alcohol, yet now we seem to think that all they have to do is put a drug on some list somewhere and it is magically prohibitive.
The constitution imbues the Federal Government with the power to protect the United States from enemies, foreign and domestic. Drugs fall into that category.