How would you, personally, "profit" from such a thing?
First of all, red states would no longer be RED, the exodus would probably crash the economies of the blue states, which could then easily go bankrupt, leading to defaults on all kinds of payment, with those governors then begging the Fed to bail them out.
Moving a company to a lower tax state also means that salaries get slashed.
There are a lot of other details that you haven't taken into consideration/thought about at all.
Get yer drift... was thinking more short-term, local real estate appreciation & that collapse of blue states inevitable anyway. So, hypothetically, maybe cash out short-term real estate profits, invest in precious metals, buy a sailboat and retire to an uninhabited tropical paradise?