We don’t have many MOAB’s and C-130’s are the delivery system for them. C-130’s wouldn’t get very far.
They flew one from the Atlantic coast to S. Korea non-stop in World War Z.
Certainly not going in naked. Normal tactic is SEAD first so air superiority is guaranteed.
Heck, even the nuke SIOP required tactical nuclear bombing of air defenses so the B-52s could come in high enough to drop the crowd pleasers.