It wouldn’t surprise me if Mueller does resign due to the conflict.
But don’t expect whomever Rosenstein replaces him with to be any better or any less committed to using the Special Counsel’s office as a fishing expedition to investigation all of Trump’s businesses and other activities to find something, anything to base a Dem/GOPe impeachment effort on.
I tend to agree.
If Mueller has any integrity at all which I think he has he'll resign.