[fishtank]

From the article:

” However, we now know that this just isn’t true. Antibiotic-resistant genes existed long before people developed antibiotics.

I first wrote about this more than five years ago, when researchers found bacterial, antibiotic-resistant genes in permafrost alongside mammoth genes.

Obviously, people weren’t making antibiotics when mammoths were alive.

Thus, those genes existed long before human-made antibiotics. Later, I wrote about....”

[JohnBovenmyer]

Thus, those genes existed long before human-made antibiotics.

Many of the 'human-made' antibiotics were initially isolated from bacteria, fungi and other organisms Those weren't novel agents although the context and quantity of their use was changed by humans.