The best that can be obtained is delay. "The plan" for more centralized global government is not some firm or rigid blueprint, it it an idea that will be pursued by aristocratically-minded people, for as long as people exist.
We can slow it down and pray that God intervenes and spoils their challenge to His authority. World domination by one ruler or one entity to is a direct attempt to usurp His power over His creation. Either way, it will not end well for them to pursue this realm of world domination.
They are deliberately destroying healthy civilizations to elevate themselves to power; they will be punished.