Like the Brewster Buffalo on Wake Island versus the Mitsubishi Zero? That much difference?
The Curtiss JN-4 Jenny wooden and fabric biplane was an American built trainer aircraft built during the First World War beginning in 1915, and it was too poor in performance in 1917-1918 to fly against almost any fighter aircraft in use during those years. Its maximum speed was 75 mph, and its cruising speed was 60 mph.
The North American P-51 fighter aircraft and metal monoplane construction produced in the period 1942 and later operated at speeds from a maximum of around 437 mph and cruising at 362 mph.
Upgrade as they will, an Iranian F-14 is to an F-22 as a Curtiss JN-4 would be to a P-51D.