Obviously, the Babe, with 714 by his retirement in '35. But, from memory, can you name the other? Hints below:
American Leaguer
Righty
First baseman
primarily Philadelphia Athletics, then Red Sox, finally short stints with Cubs & Phillies
"There's no crying in baseball."
"Double X"
http://www.baseball-reference.com/players/f/foxxji01.shtml
Jimmie Foxx, “Double X,” also known as “The Beast.” With so many regular players called to the armed forces, he did a comeback stint during the war. But he wasn’t what he had been.
Watching the All Star Game with my son, we went down the lists of top 4 players for each franchise with me guessing the players. Foxx was the first member of the A’s I named and my son gave me that “how do you know this stuff” look.