I went a few years ago to see the inner harbor, ships and Fort McHenry. The Constellation was just returning from a multi-year refit and there was a big celebration with fire boats spaying and a National Guard unit firing artillery salutes. We enjoyed it.
Never going back.
After CPAC in 2008, I went to Baltimore to see the Inner Harbor, the Constellation, Ft. McHenry and the church where the hymn Jesus Saves was first performed--which is across a park from where H. L. Mencken lived.
I thought Little Italy was touristy and overpriced, but I did manage to find a good Italian dinner.