Lasers can be used but they require so much power and chemicals, they can work against ballistic missiles but for cruise missile, I’d favor the use of the Phalanx Gatling gun or some sort of anti-aircraft gun based system much like World War II, better than nothing. I think maybe a SAM can knock them down. Perhaps barrage balloons can help.
A ballistic missile must survive, what? Oh yeah, lots of heat. Gee, what does a laser bring to the fight? Figure it out and get back to the discussion.
CIWS needs some thought as to end game as well, particularly with super/hyper-sonic missiles.
OK, you blew the missile into pieces. But, now, instead of a missile with warhead, you have a shotgun blast coming at you at supersonic speed, in your thin skinned aluminum ship.
I saw pics of what an unarmed target drone did to an aluminum destroyer. These modern ships are not the WWII ships as far as ability to take hits.
Standoff missile defense is all the navy has, and unfortunately, they cannot carry that many missiles. The Russians figured that out decades ago the trick was to come up with 360° attack swarm to swamp defenses.
Sucks, but defending a ship these days is a dismal task against the Russians/Chicoms. Once out of missiles, out of luck.