“Most assassins, spies, hit-men, etc. use .22s.”
That’s good work if you can get it but not much good for defense agains’t the Michael Brown kicking in your front door. :-)
If Michael Brown is at your door you grab a shotgun or rifle. The PT22 is to carry with you. But if you only have one pistol, it'd be better than nothing. Actually, if Mike comes to my door, I'm going to have fun and teach him a lesson about quarterstaffs.