Colt Python .357 myself, arguably the best all around revolver ever made IMHO and what I carry and keep in my desk here.
If I had to choose an automatic the Colt 10mm I have is quite nice also, but not nearly as reliable ever as their revolver, and that is what is most important to me.
Mine is the little 4” bbl. S&W model 19. Bill Jordan’s idea to beef up the K frame but I carry a .380 Mustang colt as at my age carrying anything heavier makes me list.