Autonomous Vehicles driving on rural roads/highways during whiteout winter conditions will be problematic.
I know it is fiction, but if you have seen iRobot, these robots will make decisions based on mathematical computations to decide who lives and who dies in a crash.
Why? Depending on the sensors, they may be far better at sensing the road and other vehicles than a human in those conditions.
And if not, they will probably be programmed to slow down, pull over and not drive in those conditions, where humans often will endanger themselves and others.