[ROCKLOBSTER]

If they blew the cockpit door off that resulted in cabin decompression that eventually lead to a dead crew and passangers,

Or maybe they "use enough dynamite there Butch?" and took the complete nose off the aircraft. And unlike Flight 800, it flew straight and level for hours.

[Usagi_yo]

I think it just simply got shot down by somebodies military over there.

[ctdonath2]

If they’re deliberately blowing doors off an airplane in flight, they’re not concerned about transponders continuing to function.

Kinda like trying shooting the driver of a bus, and still being concerned about removing the license plate.