40-50 below won’t kill you instantly. They probably wouldn’t even pass out from the low oxygen since they would be low enough within time.
The shock from the explosion (my guess) would probably stun most of them.
They would have lost consciousness within seconds from the rapid decompression and hypoxia. Some might come back closer to sea level.
The metal and composite aircraft shreds into a million pieces that become meat grinders. It is a very, very messy event and in addition the immediate exposure to 550+ mph winds tends to take people apart. Any that survived that I am sure were unconscious for their ride down.