I have my sights on Santiago, Chile after the SHTF. The Panama Canal will close (too easy for raiders to prey on ships) and Valparaiso will once again be the first Pacific port for ships making the trip around Cape Horn. Chile is a very nice country and the people are as (or more)industrious as most Americans.
Medellin is gorgeous and as secure a place as a lot of places here.
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Probably safer than many U.S. cities like Detroit, Baltimore, Memphis, etc.
I have also had my eyes on Chile. Excellent climate (depending on the latitude), no real natural enemies, stable economically, stable and relatively non-corrupt politically.