So you would throw out Ted Cruz and Mike Lee amongst others? Great strategery genius!
While it might be tough to lose Jeff Sessions & Jim Inhofe, I think we'd be better off without McConnell, Collins, and Graham if the other side was losing Levin, Durbin, Harkin, and Rockefeller.
Even if Lee & Cruz had to be sacrificed, clearing out these entrenched little gods of Washington would be well worth it in the long run.