There will be no significant entitlement cuts under this President. Further, Ryan is offer to dilute the sequester as part of that deal, a step backwards. Also, controlling the Senate won't help kill Obamacare, since there will be a Presidential veto until January 2017. I guess you could horse-trade it for another socialist on the Supreme Court, but I'm sure you would not favor that. Finally, Ryan's position on immigration is anathema to the country's best interests.
Paul Ryan lost me when he watered down his budget proposal in March of last year to position himself under Mitt Romney's wing. We see where that straying from principle got him.
Ryan lost me when he started promoting Amnesty for Illegals.