One report had the UPS plane on fire before it crashed. MANPAD?
Report was from CNN from someone at the crash scene.
Quote from CNN article:
Witness Peter Torres, a Civil Air Patrol member who said he is a former airline mechanic, said he thought he heard what sounded like a backfire from the jet's engines as the plane passed overhead. He rushed to his window."I saw the flash," of an apparent explosion, he said, followed by a "boom" that shook his home.
I guess the flash and 'boom' were the plane crashing (impact)...
It could be, but know that explosion-before-crash and on-fire-before crash are commonly reported in error by eyewitnesses. Unless the eyewitness is aviation-savvy, such reports must be treated with caution.
I'm not getting an impression of foul play so far, but if there is any, I'd rank the odds of booby-trapped parcel above missile.