Geez, lots of new senators gone right after an election, DeMint, Kerry, Inouye.
Kerry was last re-elected in 2008...so his seat, whoever would fill it, would be up in 2 years, same as DeMint/Scott. Inouye was last elected in 2010 so his replacement will probably be by special election, since it has 4 more years. Not certain of the last...but I know one of these three would require a SE.