Angle was unelectable, her prior record of losing races demonstrated as such. Akin, however, was very electable... until he said something unbelievably stupid and then was followed by Mourdock in IN. If these candidates don’t have enough common sense to know what to say and what not to say in public, no amount of support from Conservatives is going to overcome that on Election Day.
By all rights, Warren was unelectable, but she defeated a good candidate, Brown. With enough party support you can elect a dog as dogcatcher. Angle was, in the end, shot down by the country-club set who support only their own.