Holder will not resign, no way, and if Obama is reelected Holder will remain attorney general unless impeached and convicted by congress, which is in their authority to do.
This, however, does not mean he escapes justice.
The best bet would be for president Romney to appoint a real “hard-ass” to be the next attorney general, with instructions that he both purge the Just Us Department of scoundrels, criminals, radicals and Islamists, and replace all federal district attorneys with equally “hard-assed” individuals, to restore credibility to the justice system.
And this will be just one federal agency that needs a major purgative. Just finding enough honest “hard-asses” to replace the profligate numbers of scoundrels in the executive branch will be a major undertaking.
How about tapping some of the officers from the wars in the sandpiles? Many of them have years of experience dealing with lying Muzzie scoundrels. Who would be better suited to removing the subversives? I bet Allen West could name you a dozen off the top of his head.