The chances of either winning the popular vote but losing the electoral college are exceedingly slim. There is only one example of this happening in modern history.
it’s very difficult to win the popular vote by more than half a percentage point in yet still lose electoral college that does not happen
actually there are two; Harrison beat Cleveland and Bush beat gore in that fashion.
Not to mention that, Republicans are greatly overrepresented in the electoral college. There is a virtually zero chance of a Democrat winning electoral college but losing popular vote.
Beyond simple representation, people tend to think that states are little containers of isolation, but that just isn’t the case. You can’t win NC without winning NC, and you can’t win VA without winning NC, and so on. It’ll never happen. Just never.