The present track and strength estimates have Isaac putting a major hit on the Keys.
Way back in 1986 - 1987, when the world was young(or at least I thought so), I was in the USAF stationed at Key West Naval Station, Truman Annex. I was considered essential personnel (communications), and would have had to stay at my post during a hurricane. You can bet I sweated out those hurricane seasons.
Why? You were in a safe place, with every assurance available from modern technology and a vast organization interested in your welfare. Did you have property at risk? Family? If not, it was just a hurricane party for you. Why the anxiety?