Not necessarily. Different people respond differently to different types and concentrations of irritants. I am practically immune to CN, but oleoresin capsicum puts me down. You also have to consider the amount of time it would take a dispensing canister to become effective in a large room such as a theater. There’s a window of at least several seconds in which to act.
Ah, you’re one of those lucky ones. That stuff puts me on my ass in a flat second.
Good point about the billowing time factor. Of course, if he didn’t start shooting until it was billowing, then that would make it that much harder to respond. Regardless, that’s not a place you’d want to be even if there wasn’t a shooter.