The ancient gene codes for a protein that apparently works fine - once the genes for the proteins it binds to evolved (de-evolved?) to better interact with it.
It is a very interesting finding. Not entirely unexpected -genes for proteins that interact often evolve in parallel, with a change in one that confers a temporary advantage necessitating a change in the other to better interact.
The basic premise of a sci-fi/horror movie is....
humans mess with nature
disaster results.
Like a Homer Simpson philosophy of “Kids, you tried your best and you failed miserably. The lesson is, never try.”