Depends on how you use them. If you navigate with IE (will the latest patches) to unknown websites you will eventually get zero-dayed, no doubt about it. With Safari, that is not as likely, but still possible.
How so?
Given that IE 9 is more secure than Safari.
The myth of the “safe” OSX has long been destroyed:
Mac Virus Infects Over Half A Million Computer
http://thebottomline.as.ucsb.edu/2012/04/mac-virus-infects-over-half-a-million-computers
Widespread Virus Proves Macs Are No Longer Safe From Hackers