Cisplatin is nasty stuff. It nearly killed me. Then it saved my life.
I have some personal exposure to chemotherapy due to my Labrador Retriever developing cancer late in life. I could afford it at the time, and he was my baby so to speak, so I had him treated for it. Nothing that would make him miserable or sick. The most beneficial thing we did for him was carboplatin and then radiation treatment of the tumor. Not sure why the two were regarded as somehow synergetic, but that’s what I recall. He was never sick, didn’t lose his coat (dogs typically don’t unless they’re a breed noted for not shedding) and the cancer was in retreat. He died of other causes, almost fifteen years old, happy as a clam until the day he died. Still miss him, always will I suspect.
Cisplatin is a harsh one, carboplatin not so much, at least for dogs, which are similar in many ways to humans as far as reaction to chemotherapy and responsiveness to it. There was another that we were going to introduce into the regimen before he died, can’t recall the name but it’s made from something natural. I want to say avocado pits, but that’s that controversial thing from the seventies, laetrile? Not it, but the origin is close.