There is no protein in smoke so there can be no allergic reaction.
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Must protein be present for all allergic reactions? I have been reading up on allergies, am allergic to pollen ( mild these days ) and many uncooked fruits.
I just read about the protein aspect of allergies two days ago but was uncertain if it must exist in all cases of allergies.
Think about what causes a hystimine reaction. I assume you studied that much.
It has to be a molecule large enough to hit the receptors and activate them.
/johnny