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To: allmendream
Now why do you suppose a bacteria would have an error prone DNA polymerase that would be expressed during stress?

Do you not understand English? I answered that. The cell does not have arms and legs to build shelters. It must use itself to muster a defense. It is part of the previously established stress response.

You obviously have no interest in attempting to listen to any concept counter to your preconceptions because you did not avail yourself of the opportunity of seeking who James A. Shapiro was. Well, here is a link to an 1:38 minute lecture taking to task your simplistic views. James A. Shapiro - Revisiting evolution in the 21st Century

shapiro.bsd.uchicago.edu/2010.WorksOfTheMind.pdf

shapiro.bsd.uchicago.edu/Shapiro.2010.MobileDNA.pdf

I can see why you would be confused and ignorant enough to think that made some sort of point for you - but it doesn't.

That is because you are the one confused. The DNA polymerase in no way is directly involved in the actual response made to the stress. It allows a response to be made. It is akin to providing the paper for "War and Peace".

Anyway, listen to the lecture. The process is established prior to the stress.

380 posted on 10/06/2011 4:18:20 PM PDT by AndrewC
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To: AndrewC

By “use itself to muster a defense” you mean increase its mutation rate in order to ‘find’ genetic solutions to the stress?

Error prone DNA polymerase is expressed via transcription factors that are activated during the stress response. It is DIRECTLY involved in the actual response made to the stress because it DIRECTLY introduces mutations that ARE the response that is made.

The process IS established prior to the stress.

Why, are you ignorant enough to STILL insist that all cell stress leads to cell death?


383 posted on 10/07/2011 7:54:16 AM PDT by allmendream (Tea Party did not send the GOP to D.C. to negotiate the terms of our surrender to socialism.)
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To: AndrewC

The stress response that includes expression of error prone DNA polymerase is about as good an example as one can find of what Shapiro is talking about when he says....

“Novelty in evolution comes in part from genome changes that are the result of regulated cellular activity”

Regulated cellular activity = the stress response.

Genome changes = the result of using error prone DNA polymerase instead of the usual high fidelity DNA polymerase.

Novelty in evolution = a novel solution to the stress brought about by increasing genetic variation and allowing selective pressures (stress) to act such that particular genetic variations (those better able to thrive during the stress) predominate.


385 posted on 10/07/2011 7:59:32 AM PDT by allmendream (Tea Party did not send the GOP to D.C. to negotiate the terms of our surrender to socialism.)
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