Or they may just have taken a local bus south on fourth to the Grayhound terminal. Sorry, you will have to argue with my wife who was raised in ABQ / Rio Rancho.
Wow, well your wife may be a bit off. Shall I list off all of the I-25 exits that are MUCH closer to I-40, or north of Osuna?
And, Osuna is a really long, barren drive. So, yes, unless they were grabbing a local bus downtown, to get on greyhound (although there would be much better and closer places to drop off the truck than this location), they are a long way from I-25.