Essentially, you can be sealing in the moisture, preventing it from escaping. And I understand that radon gas poses a far greater risk in houses that are well sealed and insulated, because the gas can't disperse as it does in "leaky" houses.
Don’t get me wrong. Tight, well-insulated, well-ventilated structures are always best.
What causes problems is changing one or two elements and not working thru how they will affect everything else. Change one part of any system and it can affect other parts, often in unpredictable ways.
I’ve seen beautiful century-old victorian homes that had been neglected for decades but despite this were still structurally sound begin to literally rot away within two years of being refurbished, insulated and caulked.
We have adequate insulation overall but our house is NOT over-insulated like a thermos bottle. In our circumstances, I believe that would be undesirable.