Those are pretty amazing numbers for a relatively-unknown Republican in Massachusetts. Suffolk County is a lost cause for any Republican, no matter how popular, containing as it does the neighborhoods of Allston and Brighton (young college students living in overpriced, squalid apartments on daddy's dime) as well as Dorchester, JP, Mattapan, and Roxbury (where you could light off a neutron bomb and not a single Republican voter would be harmed). Of course, there's also Southie, where I'll bet Scott will pick up a good number of votes, but not enough to make up the difference.
The women's vote is undoubtedly tough for any Republican in the Bay State owning to a few enclaves in the western part of the state (Northhampton and Amherst for example), largely populated by females in plaid shirts and work boots with lots of turquoise and silver rings, if you get my drift.