So would you then be an advocate of replicating trained Star Fleet crews?
No need. The M5 computer was capable of running a starship back in the day (TOS: The Ultimate Computer). Granted, it occasionally went insane and tried to kill everyone on your side (probably a Windows problem) but they've had 80 years to work out the bugs.
If that doesn't work, just staff each ship with robots. While Data is cutting-edge technology, surely it would be easy enough to make robots that aren't sentient but could perform their tasks adequately. Even if they aren't as efficient as humans, the sheer number of ships will overwhelm any enemy such as the Borg.