Self defense by the driver against someone in the BACK of the pickup? Only on tv, unless he had a gun.
Dude didn't jump in the back for a ride to the 7-11. It seems likely he was pissed and trying to get into the cab. He could probably kick the back window out pretty easily. If so, under those circumstances I could easily understand self-defense.
If I'm defending her "self defense" never comes up at trial. She was fleeing an assault and his death was incidental to her flight.