In thinking about the founder’s fear of confederacies, we must consider that they were concerned with future civil wars between such confederacies. We fought one over slavery. Imagine another over state’s powers?
bttt
The storm clouds over slavery were in the air over slavery even when John Jay wrote Federalist 2. The founders were careful enough to limit federal powers enough that the war would not start for 75 years.
In 1785 Jay and a few close friends, mostly slave owners, founded the New York State Society for Promoting the Manumission of Slaves (see Minutes of the Manumission Society of New York, v.1, 1785). The Society entered lawsuits on behalf of slaves and organized boycotts. Jay also advocated subsidizing black education. I consider education to be the soul of the republic, he wrote to Benjamin Rush in 1785. I wish to see all unjust and all unnecessary discriminations everywhere abolished, and that the time may soon come when all our inhabitants of every colour and denomination shall be free and equal partakers of our political liberty (see John Jay to Dr. Benjamin Rush, 3/24/1785, Jay ID #9450). In 1787, he helped found New Yorks African Free School, which by December 1788 had fifty-six students and which he continued to support financially (see John Jay to John Murray, Jr., 10/18/1805, Jay ID #9603). By the time the Manumission Society surrendered management to New York City in 1834, the school had educated well over 1,000 students.
http://www.columbia.edu/cu/lweb/digital/jay/JaySlavery.html
Yea, so they created a BIG GUBMINT that was supposed to prevent faction, sectionalism, and civil war. Instead of preventing it, it led directly to it! Typical government program.