You really should stick to your areas of expertise and not draw conclusions from skimming a Google search. Mitochondrial Eve has been determined to have lived between 150,000 and 250,000 years ago. That is a minimum of 7,500 generations ago. Your "hundreds" number is derived as the interval between SNPs (single-nucleotide polymorphism).Mitochondria within the cell have nearly identical DNA sequence. Within the human gnome about once every 4,000 years a stable mutation occurs in a female that is passed to a female offspring and thus can be passed to subsequent generations. This equates to the 200 generations you were bloviating about.
Which would be astrophysics?