From the 2008 Annual Report:
"In 2008 MDA allocated $162.4 million to research, health care services, and professional and patient health education. Of every dollar MDA spent, 78.3 cents was dedicated to program services. Fundraising costs accounted for 14.1 cents, and management costs were 7.6 cents. MDA is accredited by the Better Business Bureau, and has been listed as a Top-Rated Charity by the American Institute of Philanthropy."
Seems ok to me. I have used 75% in the past as the don’t donate point. Read something about that maybe 20 years ago.