Bad science marker!
I wouldn't be so quick to dismiss it, especially if it is reproducible.
In humans in vivo, such changes in shear stress can be experimentally determined by inflating to suprasystolic pressure a pneumatic cuff around the forearm for 4 minutes and 30 seconds. Upon release of the cuff, the sudden increase in blood flow (and shear stress) that follows reperfusion is a potent stimulus for endothelium-dependent vasorelaxation, which can be observed using ultrasounds [6, 7]. In sum, the endothelium shows measurable responses to flow changes, determining endothelium dependent, flow-mediated dilation (FMD). These measures might have a clinical potential, as several studies show an association between impaired FMD and poorer prognosis [2–4].