The stakes are higher, of course, than just gun rights. If the judiciary somehow breathes new life into the Tenth Amendment, and curbs federal regulation of commerce taking place entirely within a state, that would let states bypass innumerable federal rules on everything from pharmaceuticals to children's toys.Exsqeeze my ignorance but I'm 99.995% sure the Rehnquist Court over turned a lot of laws just because of that. In effect they told Congress, "The Commerce Clause doesn't pertain to everything." (iirc that was in regards to Di-Fi's Gun Free School Zone Law they overturned).
And in this article Justice Thomas basically says the same thing: ""If Congress can regulate this under the Commerce Clause, then it can regulate virtually anything."
In its Lopez decision, SCOTUS told Congress how to write a gun-free-school-zones act that would survive SCOTUS scrutiny. Congress followed the advice, and DiFi's Gun Free School Zone Law is currently on the books and enforceable.
SCOTUS is not at all friendly to the RKBA, nor is it at all friendly to diminution of federal power against the states, or against the individual.