I’m not the one trying to be a smarty. I was just telling you what I know.
If you are already wise from experience, why bother asking?
Try explaining what YOU know instead.
Of course delivery method and dose matters. That’s something that’s tailored to meet each individuals needs. Nothing that works for one person is guarantied to work for another.
Sorry....you just seemed so set in your beliefs....I had to do a years worth of research....premarin and many hormones are given in PILLS.....they go thru the LIVER....which doesn’t make sense....that’s not where they are needed, and hormones do not NATURALLY go through our livers, other than the ones the LIVER needs. Also, with Premarin...a SURGE of hormone happens in the hour or two after the pill which is probably the cause of many of the problems that come with it. Bio-id creams compounded for the individual are put on the labia and do not go through the liver, but go directly (or as closely as possible) to the sexual organs needing those hormones....over a much slower time frame.
Balance of hormones is important too....you can’t just take some estrogen.....you need to test DHEA, Pregnenelone, Testosterone, Progesterone, and Estrogen.
Here’s an interesting article from my doctor, Dr. Jonathan Wright....http://www.tahoma-clinic.com/hotflashes.shtml
But, that article BARELY touches the research he’s done. Hope that helps. I, as you can tell, am passionate about this...having dealt with many ignorant doctors.