Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer.
It's a lentivirus method of gene therapy. Sixty two percent of the mice had no response or worse, i.e. graft versus host disease or host versus graft disease. Cancer patients are already considered immunocompromised. Any requirement for immunosuppressant drugs would increase morbidity and mortality, IMHO.
Rose Bengal ......Target and destroy the deadliest cancers – melanoma, liver & breast – while eliminating side effects. Clinical trials for metastatic melanoma and recurrent breast carcinoma are currently underway.
Provectus has developed groundbreaking biotechnologies to augment vaccine production and detect viruses (including an innovative “virus hunter” method)
KNOXVILLE, Tenn.--(BUSINESS WIRE)--Provectus Pharmaceuticals, Inc. (OTCBB: PVCT, http://www.pvct.com), a development-stage oncology and dermatology biopharmaceutical company, announced today that a poster, Abstract #9060, entitled "Chemoablation of melanoma with intralesional rose bengal (PV-10)", will be presented on June 1, 2009 in the 8:00 a.m. - 12:00 p.m. General Poster Session (Group F, Brd. F15), at the 2009 American Society of Clinical Oncology (ASCO) Scientific Program at the Orange County Convention Center in Orlando, Florida.
Dr. Sanjiv S. Agarwala, Principal Investigator for Provectus' Phase 2 PV-10 trial site at St. Luke's Hospital & Health Network in Bethlehem, PA will present an update on the development efforts with PV-10 for metastatic melanoma, including interim Phase 2 safety and efficacy data on the first 40 subjects in the trial and interim bystander correlation data on response of untreated tumors in subjects whose treated tumors responded successfully. Additional Phase 1 survival data will also be presented.
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