When we learn it: After his first encounter with the Predator who has just killed his squad-mate, Mac picks up old painless and peppers the nearby shrubbery with bullets. The rest of the team soon joins in.
Why it's important: It takes a whole hell of a lot of bullets, but one finally catches the Predator, spilling some of his blood and providing an important clue. It's not the most efficient model for getting things done, but it's a lot better than sitting back and doing nothing.
I liked this bit in the movie, but I get a different lesson from it. If your buddy starts shooting into the woods, don't interrupt him to ask what he saw or what's going on. Just get out of his line of fire by standing next to him, fire at what he's aiming at, and then when its over, then you can ask him what it's all about. But in the meantime, trust him, its important.