I understand your concern on the L.O.S.T. situation. If she takes a position as a national candidate contrary to the interests of U.S. sovereignty, that would be a major problem for me. I don't think she will but will keep an eye on it.
If we can't change Congress in 2010 and get Obama out of the White House in 2012, none of it may matter anyway. And as Scott Rasmussen says in this article (and I agree completely with him), the GOP leadership is utterly lost right now.